Lamp5 marker
Tīmeklis2016. gada 2. dec. · We first confirmed LAMP5 expression in human leukemia cell lines by immunoblot and RT-qPCR assays. We readily detected LAMP5 mRNA and … Tīmeklis2016. gada 2. dec. · In leukemia cells, using immunofluorescent confocal microscopy we detected LAMP5 in the perinuclear zones where it co-localized with ERGIC-53, a …
Lamp5 marker
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TīmeklisLysosome-associated membrane protein 5 (LAMP5), also known as BAD-LAMP, UNC-43, and C20orf103, is a new member of LAMP family. It is a transmembrane glycosylated protein localized in the ER-Golgi intermediate compartment (ERGIC). LAMP5 shares sequence and structural homology with the canonical LAMP1 … TīmeklisAcross ferrets, mice and primates, the same four genes (SST, PVALB, VIP and LAMP5) were expressed in non-overlapping subsets of neocortical interneurons and together …
Tīmeklis2024. gada 1. nov. · The Lamp5, Vip, Serpinf1 and Sncg subclasses are represented by four interconnected neighbourhoods in the constellation diagram (Fig. 5b). TīmeklisFor inhibitory cells, we identified cells from the four major classes (Sst, Pvalb, Lamp5/Id2, Vip), each expressing canonical markers in the original STARmap dataset ( Figure 5 G).
Tīmeklis2024. gada 1. apr. · LAMP-5 is an essential inflammatory-signaling regulator and novel immunotherapy target for mixed lineage leukemia-rearranged acute leukemia LAMP … Tīmeklis2024. gada 28. febr. · LAMP5 is a single-pass transmembrane protein and has a role in lysosomal function. We established a stable LAMP5 knockout (KO) GC cell line and analyzed various alterations in the malignant phenotype associated with metastasis of GC to reveal the role of LAMP5 in GC progression. Global mRNA expression analysis
TīmeklisLAMP5, lysosomal associated membrane protein family member 5 Vertebrate Orthologs 3 Vertebrate Orthology Source ... Lamp5 interacts with 142 markers (Mir15b, Mir17, Mir20a, ...) View All. Sequences & Gene Models less. All Sequences. 46. RefSeq. 9. UniProt. 2. CCDS. CCDS16789.1.
TīmeklisMoreover, like in the GP, labeling of LAMP5 and the glutamatergic marker VGLUT1 showed little to no co-localiza- tion in the OB (Fig 3 E). Altogether, these data indicate that sub-populations of ... indiana primary election candidatesTīmeklis2024. gada 24. aug. · To further examine the neocortical architecture, we manually demarcated the six cortical layers guided by known layer markers (LAMP5, … indiana primary election 2022 poll hoursTīmeklis2024. gada 3. jūl. · LAMP5 limits neuronal hyperexcitation. a Latency to develop more severe seizures (left) and ranking of mean seizure severity score (right) reached within 10 min after intraperitoneal administration of 50 mg/kg pentylenetetrazole (PTZ) in 59 collaborative cross (CC; black) and 4 inbred strains (red). indiana primary election 2022 wthrTīmeklisThe "human cells" section gives an overview about the subcellular location of the protein of interest obtained by indirect immunofluorescence microscopy, an antibody-based protein-visualization technique. The immunofluorescent analysis is carried out in three different cell lines, one of them always being U-2 OS. indiana primary election 2024Tīmeklis2024. gada 17. jūn. · Mechanistically, LAMP5-AS1 facilitated the methyltransferase activity of DOT1L by directly binding its Lys-rich region of catalytic domain, thus promoting the global patterns of H3K79 dimethylation and trimethylation in cells. These observations supported that LAMP5-AS1 upregulated H3K79me2/me3 and the … indiana primary election dateTīmeklisLAMP5 is part of cluster 48 Plasmacytoid dendritic cells - Unknown function with confidence i Confidence is the fraction of times a gene was assigned to the cluster in … indiana primary election rulesTīmeklis2016. gada 7. jūn. · LAMP5 is member of the LAMP family of membrane proteins. In contrast to the canonical members of this protein family, LAMP1 and LAMP2, which show widespread expression in many tissues, LAMP 5 is brain specific in mice. In C. elegans, the LAMP5 ortholog UNC-46 has been suggested to act a trafficking … indiana primary election results