WebApr 3, 2024 · Statin-associated muscle symptoms (SAMS) are the most well-known side effects of statins, reported by up to 20% of people taking them. But this effect is much less common than people think. Muscle symptoms range from mild muscle aches to rare cases of severe muscle damage. For many people, muscle symptoms fade over time. WebSep 30, 2024 · Statins are both effective and generally safe. Although muscle toxicity remains a concern, severe myonecrosis leading to clinical rhabdomyolysis is rare, …
The Clinical Presentation of Statin-Associated Muscle Symptoms (SAMS …
WebApr 1, 2024 · With standardized questions, vetted language, easily interpreted scores, and demonstrated reliability, the SAMS aims to estimate the likelihood that a patient's muscle symptoms were attributable to statins. The SAMS-CI may support better detection of statin-associated muscle symptoms in clinical practice, optimize treatment for patients ... Web“Statin intolerance is a clinical syndrome characterized by the inability to tolerate at least two statins: one at the low- ... (SAMS), a clinical index score has been developed to capture objective information given that the frequently used biomarker to assess myotoxicity, cre-atine kinase (CK), is nonspecific and not always associated with ... craig orr obituary
Statins (research etc) Flashcards Quizlet
WebSAMSs are by far the most prevalent and important adverse event, with up to 72% of all statin adverse events being muscle related. 33 These can present as myalgia, myopathy, myositis with elevated CK (creatinine kinase), or at its most severe, rhabdomyolysis, with some people reporting additional joint and abdominal pain. 17, 34 Other … WebJul 19, 2024 · The goal in managing patients with SAMS is to get the patient on the highest tolerated statin dose, as statins are life-saving medications, and to combine statin treatment with other agents that lower LDL cholesterol and reduce atherosclerotic CVD risk ( 11 ). Patients should be reassured that SAMS resolve with statin cessation. WebNov 8, 2024 · Patients reported a statin adherence of 70%. Nine patients reported intolerable muscle symptoms at least once during the study, and intolerable symptom scores represented 3% of all reported symptom scores. Patients reported overall satisfaction with the study and found the SAMS scores helpful. diy christmas sweater for kids